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Gemcitabine induces CAFs to secrete exosomes containing miR-3173-5p, which inhibits the expression of ACSL4, thereby decreasing PUFA binding to phospholipids and enhancing resistance to ferroptosis in PDAC cells [41, 42]

Virgin Islands, Guam, the Northern Mariana Islands, and American Samoa is the FY 2024 percentage increase in the 2018-based IPPS operating market basket

5.2 ApoE and amyotrophic lateral sclerosis (ALS) ALS is a devastating neurodegenerative disease that affects upper and lower motor neurons in the brain and spinal cord, leading to progressive muscle weakness, stiffness, and eventual paralysis (Mead et al., 2023

[DOI] [PMC free article] [PubMed] [Google Scholar] 211.Trasino S.E., Benoit Y.D., Gudas L.J