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The nasal mucosa provides an efficient absorption site, enabling rapid systemic distribution while protecting the peptide from enzymatic breakdown

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Patients should be counseled that identifying an effective pain relief regimen may require multiple trials of different medications in order to identify the medication(s) that produce optimal effects for that particular patient

Journal of Pharmaceutical and Biomedical Analysis , 192 , 113642 Begines, B., Ortiz, T., Prez-Aranda, M., Martnez, G., Merinero, M., Argelles-Arias, F., & Alcudia, A