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Certain medicationsincluding proton pump inhibitors, metformin, and some anticonvulsantsmay affect the absorption or metabolism of specific nutrients

We identified FSP1 as this warfarin-insensitive vitamin K reductase, clarifying that the antidotal mechanism of vitamin K against warfarin overdose involves FSP1-mediated reduction of vitamin K, leading to the activation of coagulation factors even under warfarin poisoning [13, 51] (Fig

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The same case report documented biological age reduction and telomere length increase, with the patient's biological age decreasing by 7.9 years (from 75.93 to 68.03) and telomere length increasing from 6.45 to 6.59 kb over one year of treatment