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[31] The products are usually extracted and purified by phenol-methylene chloride extraction or by column chromatography

Cell 85, 638651

Or is it just a passing trend

Topical and microinfusion-delivered PDRN is the newer application, with literature growing rapidly since 2020

Sample tissue characteristics: the structure and function of cells in different tissues vary, and proteins that are stably expressed in that tissue should be selected as internal references