In the present study, we carried forward these four ACs and tested whether the relationships with depression predicted from genomic data (negative with C2 and C3, and positive with C8 and C10) were expressed in actual phenotypes measured in a large cohort (N ~ 2500) with extensive clinical phenotyping
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Leukocyte-derived ROS, particularly in the context of infections and inflammation, can induce lipid peroxidation, DNA fragmentation, and protein oxidation, all of which contribute to reduced sperm quality and male infertility
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