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Insulin-like growth factor-1 regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways

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Oxidative stress is also a natural process, but like inflammation, when its out of control, meaning in this case, when theres an imbalance of free radicals compared to antioxidants in the body, cell and tissue damage can occur

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