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This is a mechanism by which a company can argue that a new product is similar enough to an existing one to be marketed without further safety testing

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Other studies have identified comparable rises in arterial stiffness between combustible tobacco products and ENDS containing nicotine as an observable rise in arterial stiffness, which was noted for 15 min after using either product [73]

Chinese Center of Disease Control and Prevention

Women with a family history of breast cancer, especially if a close relative was diagnosed at a young age, face a higher risk