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However, recent animal studies have produced evidence that strongly suggesting that the severe physical and psychological stress of combat may produce conditions that disrupt the integrity of the BBB , allowing pyridostigmine to penetrate into the central nervous system and produce neurotoxic effects (Friedman et al, 1996

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Kosek), the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme under the grant agreement no

10.3389/fimmu.2021.807648 58 KimY.-C.SeokS.ZhangY.MaJ.KongB.GuoG.et al (2020)