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Mechanism Involving Nrf2-Keap1 Complex Mitigates the NLRP3 Inflammasome in PD In PD, the NLRP3 inflammasome acts as a central driver of neuroinflammation, perpetuating a self-sustaining inflammatory loop that accelerates the degeneration of dopaminergic neurons

doi: 10.1016/j.immuni.2014.06.008 86 BiswasSKMantovaniA

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A typical schedule involves getting vitamin B12 shots every other day for about two weeks