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Chemically, Nigella sativa seeds contain a complex mixture of bioactive compounds, including essential oils, saponins, alkaloids, carbohydrates, proteins, and fixed oils

doi: 10.1371/journal.pone.0182372 275 ReaI

Neuroradiology 44 , 689694 (2002)

promote the proliferation of granulosa cells by reducing the apoptosis process leading to cell death support the oocyte maturation that was impaired in this mice model promote the synthesis of sex steroid hormones Other in-vivo studies have demonstrated the benefits of curcumin in supporting follicle development and steroidogenesis (33-35)

This gives a concentration of 25 mg per ml , which works out to 0.25 mg per unit on a 1 ml insulin syringe