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N3 bears a lactam ring, an aliphatic isobutyl group, an isopropyl group, a methyl group and an isoxazole as the side chain for the P1P5 sites, respectively

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notably described that the substitution of the first 290 residues of MRP1 by the corresponding residues of MRP2, like in chimera M1, leads to a complete absence of addressing to the plasma membrane with a retention in the endoplasmic reticulum 19

During this window, lyophilized BPC-157 is effectively stable