Wang C, Chen YW, Zhang L, et al
Protein S -nitrosylation, the covalent attachment of nitric oxide (NO) moiety to the reactive thiol group of a cysteine residue to form S -nitrosothiol is an important PTM for most classes of proteins ( S -nitrosylated proteins such as Bcl-2, p53, HIF-1, PTEN, and Src are involved in cell survival, angiogenesis, tumorigenesis, and response to cancer treatment (68)
Statements Author contributions WT: Conceptualization, Project administration, Supervision, Validation, Visualization, Writing review & editing
This comprehensive approach addresses multiple wrinkle mechanisms simultaneously rather than targeting only one pathway
Nayan Patel: Not anymore, Okay, Good