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In case of organic disease, that affects the terminal ileum (e.g., Crohn's disease, ileal resection, etc.), bile acids are not absorbed and enter the colon, where they induce diarrhea

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Monitoring Progress: Regularly follow up with your healthcare provider to monitor your progress and assess the results

Human evidence - Phase 3 TRANSCEND-T2D-1 (Eli Lilly, March 19, 2026) 537 adults with type 2 diabetes, randomized 1:1:1:1 to retatrutide 4, 9, or 12 mg or placebo

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