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doi: 10.1097/00006842-199503000-00013

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1, 3 The antibodies against thyroperoxidase (anti-TPO), antithyroglobulin (anti-Tg) and more rarely TSH-stimulation blocking antibody (TSBAb), are positively correlated with an increased inflammatory reaction in the thyroid and with the development of Hashimotos disease

Moreover, mtDNA and nuclear DNA in the mitochondrion cause it to receive the regulation of two sets of genetic information, and may also get the mutation of two kinds of genome, making the treatment more complicated

This cell-based assay starts with the modification of protein free-thiols groups followed by enzymatic cleavage of any protein-S-glutathione (PSSG) adducts present in the sample