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Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors

Simultaneously, AMPK suppresses the nuclear translocation of sterol regulatory element-binding protein 1c (SREBP1c), downregulating the expression of key lipogenic enzymes such as fatty acid synthase (FASN) and stearoyl-CoA desaturase 1 (SCD1), thereby inhibiting de novo triglyceride (TG) synthesis

I recommend 1,500 mg up to three times a day of the Meriva-SR form, which is much more bioavailable than other forms of curcumin

Journal of Biological Chemistry, 255 , 95309533

Mixing them creates stability and degradation issues that compromise the efficacy of both compounds