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The study performed in order to find the safe upper level of total daily iodine intake among Chinese adults revealed that subclinical hypothyroidism developed in initially euthyroid individuals who were taking for 4 weeks a daily dose of at least 400 g iodine (as KI) as a supplement (which, together with a diet, provided a total iodine intake of approximately 800 g/d) [199]

We might therefore predict that other metabolites would also exhibit reductions correlated with reductions in glutathione and glutamate

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