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The effects that sit outside the trial tables Menstrual-cycle changes are widely discussed in patient communities, including irregular or doubled cycles during rapid loss. Trials did not pre-specify them, so the adverse-event tables cannot estimate incidence

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GHSs : After a 16-week cycle, a user might drop the dose to the beginner range and only inject 3-4 times per week, or cycle off completely for 4-8 weeks