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The intense withdrawal symptoms and the need for long-term treatment and recovery make it one of the hardest drugs to overcome

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With fewer than 50 diagnoses in the U.S

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The well-known genetic factor related to COPD is the deficiency of serine protease 1-antitrypsin (AATD), a hereditary disorder, which increases the risk of 13% of individuals developing COPD, especially in those who smoke [47]