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The virus-induced hypoxia/Warburg effect could potentially compromise endocrinal, cardiovascular, neurocognitive, gastrointestinal, pulmonary, and reproductive functions that demand high levels of mitochondrial O 2 consumption, OXPHOS, and ATP reserve

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This is especially relevant for people taking anticoagulants, immune-modulating medications, or multiple prescription drugs

In chronic retinal diseases, maintaining M2 phenotype protects neurons from immune-mediated injury

The enzyme that cleaves the extra glutamates from folate so that it can be taken up into the enterocyte is a metalloenzyme3