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Potential Research Applications: Immune modulation and enhancement studies Chronic infection and antiviral research models Inflammatory response and cytokine regulation studies Immune deficiency and autoimmune condition research

Bibcode:2016ER....151..763F

FOXO4-DRI successfully removed senescent chondrocytes, and the results confirmed that removal of senescent cells significantly increased cartilage formation potential and reduced degenerative enzyme production

Veys KR, DHauwers KW, van Dongen A, Janssen MC, Besouw MTP, Goossens E, van den Heuvel LP, Wetzels A, Levtchenko EN (2018) First successful conception induced by a male cystinosis patient