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One of the most recent contributions came from researchers at Thomas Jefferson University in Philadelphia, who in 2016 published a relevant study in the journal PLoS One

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It has been shown that the vitiligo macules are not completely devoid of melanocytes, and that their activity can be restored following the effects of some stimuli

In cardiomyocytes, a reduction in CCO activity compromises mitochondrial energy production [243]

NF-B has been suggested as a key player in exacerbating liver inflammation, as phosphorylated NF-B levels are also elevated in preclinical models of NASH (dela Pea et al., 2005