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They are also contraindicated or people with vision problems, Lebers disease, kidney failure, liver failure, folic acid deficiency or any type of systemic infection

Impaired activity of methionine synthase results in elevated blood concentrations of homocysteine, while impaired activity of L-methylmalonyl-CoA mutase results in increased concentrations of a metabolite of methylmalonyl-CoA called methylmalonic acid (MMA) in blood and urine

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Finally, dietary habits and overall lifestyle can also influence B12 absorption

Only two forms of B12 are active as a coenzyme in the body: Methylcobalamin and adenosylcobalamin are the active coenzyme forms of B12