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Gene therapy In gene therapy-based regenerative medicine, messenger RNA can be degraded to decrease the level of expression of relevant genes or exogenous genes can be inserted into cells by means of (non-) viral vectors to increase gene expression [85]

It was discovered accidentally in 1967 by German chemist Karl Clauss at Hoechst AG -now Nutrinova-

This result suggests that chronic ALA treatment had little effect on microglia with 4 months of treatment, but possibly increased microglial activation with 11 months of treatment