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Trial Registration : ClinicalTrials.gov NCT02172625 Introduction Cells continuously produce free radicals (a molecule with one of more unpaired electrons) and non-radical derivatives of oxygen (i.e

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Subsequent secondary-source reviews have proposed candidate interactions modulation of GABAergic and glutamatergic tone, possible NMDA-receptor involvement, peripheral 1-adrenergic effects but these have not been replicated in primary studies that establish direct binding or saturable transduction at a defined receptor

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