how does glutathione work as an antioxidant 9 Health Benefits of Glutathione: The “Master” Antioxidant –

doi: 10.1080/23723556.2015.1054549 14

In an antimicrobial context, this could tentatively be interpreted as ApoE playing a role in coordinating metal ions to alter A aggregation dynamics toward increased cytotoxic aggregate formation to increase As antimicrobial efficacy (either alone or in synergy with other AMPs and copper), for which ApoE4 might exert the strongest synergistic AMP effect due to its copper-A interaction and its ability stabilize cytotoxic A oligomers/fibrils (Garai et al., 2014)

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The convention in chemistry is that a thiol is the reduced form and a disulphide is the oxidised form