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Research-Use Dosing Conventions (Not a Recommendation) This section describes the dose ranges used inside clinical trials and laboratory research settings only

Gaskins AJ, Afeiche MC, Wright DL, Toth TL, Williams PL, Gillman MW, et al

The guidance also listed approaches that can improve diversity of enrolled participants, including This Appendix offers a brief overview of trends in diverse enrollment and data reporting across clinical trials, and references lessons-learned and insights from other research related to demographic diversity in trial enrollment

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Active site residues U46, Q48, Q81, and W136 are highlighted and shown as sticks