It is not naturally produced in the body and is primarily found in supplements
J Drug Deliv Sci Technol 68:102979 Ahmed S, Amin MM, Sayed S (2023) Ocular drug delivery: a comprehensive review
Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see PRECAUTIONS-Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
Comorbidities and systemic inflammation Psoriasis is now increasingly recognized as a systemic inflammatory rather than an exclusively dermatological condition
Brands like NIOD utilize a high-purity, multi-copper complex to maximize this effect, while The Ordinary offers a more accessible version with a lower concentration
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