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Zhang S, Che L, He C, Huang J, Guo N, Shi J, et al

IGF-1 makes cells grow and divide, allowing for cancer-causing cell proliferation

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Studies have shown that keratinocytes, melanocytes, and immune cells express CYP27B1 and related hydroxylases, enabling local synthesis of active Vitamin D metabolites in response to UVB irradiation or inflammatory stimuli [106, 107]