Neutrophil function in inflammation and inflammatory diseases
Studies should clearly detail and identify a firms technology at both the individual component and system levels, provide supporting literature for technical feasibility, highlight existing performance data, showcase the technologys application opportunities to a broad base of customers outside the defense space, a market strategy for the commercial space, how the technology directly addresses the Armys modernization area as well as include a technology development roadmap to demonstrate scientific and engineering viability
Notably, studies have reported that DSIP-mediated analgesia occurs without the tolerance development typically seen with exogenous opioid compounds, suggesting a fundamentally different mechanism of interaction with the opioid system
Herzenberg LA, De Rosa SC, Dubs JG, et al
The published research base is entirely preclinical (rat and mouse studies plus rat hippocampal neuron culture work)