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RCT conducted in patients with T2D showed that high doses of tirzepatide represent the most efficacious incretin-based anti-diabetes drug in terms of BW reduction 33 , sustaining the development of the SURMOUNT program to explore its efficacy and safety in the management of obesity 9

In preparatory documents for the meeting, FDA staff said that it believed the evaluation criteria weigh against placing BPC-157 on the list because there was limited evidence about the peptides effectiveness and because there are other FDA-approved treatments for ulcerative colitis

References Sikiric P, et al

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