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Psychiatry 27 , 23802392 (2022)

Protective effect of curcumin against seizures and cognitive impairment in a pentylenetetrazole-kindled epileptic rat model

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The protein thioredoxin, together with TXNRD1 (or TXNRD3), NADPH, and FAD, constitute the thioredoxin antioxidant system involved in the reduction of antioxidant enzymes (e.g., peroxiredoxins, methionine sulfoxide reductases, and ribonucleotide reductase) and of many oxidation/reduction (redox)-sensitive signaling proteins (9)

Piracetam, a derivative of the neurotransmitter gamma-aminobutyric acid (GABA), has been investigated as a treatment option for Mnire disease