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Patients with cutaneous melanoma harboring rare TRK gene fusions may benefit from therapies like larotrectinib and entrectinib, designed specifically to target these fusions (49, 50)

Notably, these changes were not attributable to active viral replication since most cells in the dataset were negative for SARS-CoV-2 RNA

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First, due to the lack of detailed individual information regarding sex, mental and physical conditions, and other concomitant diseases, subgroups that may show more beneficial effects of antioxidants could not be selected ( Conclusion In summary, this MR study provides genetic evidence of a causal association between antioxidants and multiple cancer risks in Europeans

ROS are free radical molecules that can oxidatively alter cellular compounds such as lipids, proteins, and DNA, and damage cells [10]