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combination data is nonexistent Safety first Overlapping side effect profiles create legitimate concerns about additive adverse events Patience pays Phase 3 trials for both compounds are ongoing

The serine deprivation-dependent induction is regulated by the activating transcription factor 4 (ATF4) and can be reversed by the addition of glycine and serine, but not by other amino acids like leucine or cysteine (Hamano et al., 2020)

Call to Action If you are considering the GLOW peptide protocol and want to know whether it is appropriate for your injury history, goals, and health profile, work with a qualified clinician who understands peptide therapy and connective tissue biology

Proceedings of the National Academy of Sciences of the United States of America 109 , 1128211287, doi: 10.1073/pnas.1117765109 (2012)