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A 2.5 mg track has short direct data and real-world support for stable maintainers, but continuing tirzepatide has much stronger evidence than stopping. At week 112, stepping down to 5 mg preserved 16.6% weight loss versus 21.9% on the top dose and 9.9% on placebo

Across all three waves, one feature is consistent and must be stated plainly: the systemic/injected evidence is preclinical

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Several studies have reported that soy isoflavones have beneficial effects against ovariectomy (surgical menopause) as well as diet induced metabolic complications in animal models