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For example, the PARP inhibitor olaparib disrupts the SDF-1/CXCR4 axis to impair MDSC recruitment, leading to superior tumor reduction when combined with EGFRvIII-targeted CAR-T cells (178)

Combined GLUT1 and YBX1 inhibition blunts tumor growth Next, we wondered whether targeting YBX1-dependent AMPK translation to disable energy sensing and inhibiting GLUT1-mediated glucose uptake to induce energy stress would synergistically elicit cancer cell death

The statistical significance indicated for ( a - e ) represents a two-tailed unpaired t test

Ultrasound in Obstetrics & Gynecology , 48(3), 318-332