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doi: 10.5772/intechopen.85031 504 TanakaMNakayamaJ

They regulate various processes, including metabolism, healing, and growth

As discussed in section V.E.4

However, renal uric acid excretion can mask the fact that up to ~20% to 25% of gout patients have, as one component of their hyperuricemia, elevated generation of uric acid

Furthermore, most available studies are of short duration and lack long-term follow-up to assess whether repeated or chronic IF leads to sustained alterations in thyroid function or clinically meaningful hypothyroidism [60] (Table 2)