The increased SAA within acute inflammatory process replaces with apolipoprotein A-1 and decreases the HDL mediated cholesterole entry to the liver cells which is supported by inceased levels of SAA in coronary artery disease patients
[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Katsnelson B.A., Privalova L.I., Kireyeva Y.P., Yeremenko O.S., Sutunkova M.P., Valamina I.E., Varaksin A.N., Panov V.G., Kazmer J.I
It interacts with cyclic GMP-AMP synthase (cGAS) and acts as a lactyltransferase to mediate cGAS lactylation
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Timmons T, Burt K, Chema D, Tigelaar B, Hanvy P, Wilson J, Swisher SG , Nemunaitis J, Roth JA, Merritt J, Wilson D