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Description

Step 1: aldol cleavage and intermediate formation In the first step, the -amino group of a lysine residue (Lys 132 ) in the active site performs a nucleophilic attack on the carbonyl carbon (C-2) of sedoheptulose 7-phosphate

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Simultaneously, the opening of the mitochondrial permeabilization transition pore (mPTP) releases pro-apoptotic factors (such as Cyt-c), triggering endothelial cell death

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Dual glutathione depletion enhanced enzyme catalytic activity for hyperthermia assisted tumor therapy on semi-metallic VSe2/Mn-CS

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