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206 In a placebo-controlled trial, 60 patients with stage 4 CKD who had been eating a low-protein diet for two months were assigned to add probiotic supplements providing 1 billion CFUs L

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Ma et al., 2009a)

Thus, primary evidence is supplemented by authoritative sources including NIH.gov (PubChem, ClinicalTrials.gov) and Cleveland Clinic educational materials due to limited recent peer-reviewed publications on this specific query