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In particular, folate is needed for closure of the neural tube early in pregnancy, and periconceptional supplementation with folic acid (that is, supplementation beginning one month before and continuing two months after conception) has been shown to dramatically reduce the incidence of neural tube defects (NTDs) (reviewed in 29 and 30)

However, research is not considered conclusive

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the infant will simply receive more B vitamins, and excess will be excreted in the infants urine as well