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Administration: Eye drops (RGN-259 formulation) applied 4-6 times daily for corneal applications

doi:10.1016/j.jid.2024.09.012

It is also a cautionary illustration of how much context a mechanism carries: the best-characterized KPV effect depends on an intestinal transporter (PepT1) abundant in gut epithelium, which is one reason KPV has been explored mainly for oral delivery in bowel inflammation rather than as a general-purpose systemic anti-inflammatory