Flavell, S
Autism spectrum disorder (ASD), as reflected in its abbreviation, is not a single condition but a spectrum encompassing diverse developmental profiles, co-occurring conditions, and varying support needseven among children who share the same diagnosis
Both conditions cause fatigue, weight loss, abdominal pain, rectal bleeding, bloating, and diarrhea
Overactivated M1 macrophages exacerbate inflammation through secreting pro-inflammatory cytokines, driving joint damage, whereas immunosuppressive M2 macrophages are diminished, disrupting immune equilibrium (130)
Ongoing outcome trials are expected to clarify whether its LDL-C-lowering translates into event reduction comparable to that of PCSK9 monoclonal antibodies