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Emerging Concepts in Endometriosis Pathogenesis Emerging evidence suggests that aging and chronic disease-related processes may play a key role in endometriosis beyond its classical features of ectopic tissue, inflammation, and hormonal dependence

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For example, the HNP-1 (ACYCRIPACIAGERRYGTCIYQGALWAFCC) is an AMP with extensive activity against gram-negative and gram-positive bacteria that have been shown to have low anti-tumor activity against healthy cells (114)

The R-domain is helical (residues 920929) in the C-terminal segment and lacks secondary structure (residues 901919 and 930935) in the other