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Although PPIs exhibit exceptional acid inhibition effects, various studies have linked PPI use with adverse digestive events, such as small intestinal bacterial overgrowth (SIBO) and Clostridium difficile infection

Abbreviations AKI: Acute Kidney Injury BMI: Body Mass Index VAS: Visual Analog Scale SD: Standard Deviation IQR: Interquartile range CoA: Coenzyme A NF-B: Nuclear factor-kappa B IGF-1: Insulin-like Growth Factor 1 MAFLD: Metabolic Dysfunction-Associated Fatty Liver Disease References Konikoff F, Theodor E

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