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Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease

Most common: Acne / oily skin Libido changes Mood fluctuations (including irritability) Fluid retention Injection site pain, swelling, or bruising Elevated blood pressure Elevated hematocrit, hemoglobin, and PSA (lab monitoring required) Testicular shrinkage / atrophy Gynecomastia Night sweats Serious side effects may include: Polycythemia / elevated hematocrit (monitor CBC) Suppression of spermatogenesis / infertility while on treatment Elevated PSA Sleep apnea exacerbation DVT or PE (rare

High concentrations given intravenously may be diluted using parenteral infusion solutions

The compound shows promise but remains in early stages of investigation

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