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Gastroenterology 125:117125

In addition, COF-618-Cu displays superior CAT activity (O 2 production), GPx activity (GSH depletion)

Boosts collagen production

Simultaneously, they significantly influence immune cell function, thereby creating an immunosuppressive environment that further enhances drug resistance ( Furthermore, immune cells in the tumor microenvironment can potentially influence drug metabolism and elimination by releasing specific cytokines and chemical substances, thereby exacerbating drug resistance mechanisms ( Cancer stem cells (CSCs) are a population of tumor cells with self-renewal and differentiation potential

[7] Fragment 176-191 may potentially engage additional cellular signaling pathways that indirectly promote fat metabolism