Song, M., Zhang, F., Fu, Y., Yi, X., Feng, S., Liu, Z., Deng, D., Yang, Q., Yu, M., Zhu, C., Zhu, X., Wang, L., Gao, P., Shu, G., Ma, X., Jiang, Q., & Wang, S
The co-immunoprecipitation data presented here for differentiated BCi.NS1.1 cells, cultured 16HBE14o- cells, and differentiated primary HBE cells appear to be consistent with previously reported proximity ligation experiments on model non-CF lung epithelial cells such as CFBE41o- (WT) and 16HBE14o- cells 39
Although many of these studies have based their findings on peripheral markers of abnormal metabolism, many studies have documented some of these same abnormalities in the brain of individuals with ASD, including mitochondrial dysfunction and oxidative stress (30) and one study has demonstrated a link between oxidative stress, inflammation, and mitochondrial dysfunction in the brain of individuals with ASD (23)
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