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The S tail extended motif makes contact with the binding site residues in one of the two WD40 domains whereas the upstream tail residues interact with the other WD40 domain, but at the face distal from the binding site (Supplementary Fig

Don't forget the essentials GHK-Cu (Glycyl-L-Histidyl-L-Lysine, Cu2+ copper complex) is a tripeptide of 340 Da free, 403 Da complexed with copper, discovered by Loren Pickart in 1973 at the University of San Francisco

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