While cyanocobalamin addresses nausea and vitamin status, glycine targets muscle preservation
Study has shown that it has a very good tolerability and safety, thus the immune system does not form any antibodies against the AOD-9604 peptide
It works best as one biological variable within a broader strategy that includes therapy, sleep, exercise, and where appropriate medication
Kannt A, Pfenninger A, Teichert L, Tnjes A, Dietrich A, Schn MR, Klting N, Blher M. Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. Diabetologia. 2015 Apr;58(4):799-808. doi: 10.1007/s00125-014-3490-7. Epub 2015 Jan 18. PMID: 25596852; PMCID: PMC4351435
I take cyanocobalamin as my B12 supplement for two reasons: its high stability and its track record of safety and efficacy