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Wegovy (semaglutide), an injection that is FDA approved for weight loss rather than managing blood sugar levels, contains the same active ingredient as Ozempic

Guillot A, Winkler M, Silva Afonso M et al (2023) Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression

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When miR-146a levels rise, two key TLR signaling proteins, IRAK1 and TRAF6, may decrease, and thus they may not transmit inflammatory signals inside the cell, including pathways linked to NF-B activation, which would otherwise play a major role in inflammatory signaling